Главная страница Карта сайта Контактная информация

Главная » Наука » Публикации »


J Bioinform Comput Biol. 2010 Jun;8(3):519-34. PubMed

Exclusive sequences of different genomes.

Mitrofanov, S. I.; Panchin, A. Y.; Spirin, S. A.; Alexeevski, A. V.; Panchin, Y. V.

We studied the distribution of 1-7 bp words in a dataset that includes 139 complete eukaryotic genomes, 33 masked eukaryotic genomes and coding regions from 35 genomes. We tested different statistical models to determine over- and under-represented words. The method described by Karlin et al. has the strongest predictive power compared to other methods. Using this method we identified over- and under-represented words consistent within a large array of taxonomic groups. Some of those words have not yet been described as exclusive. For example, CGCG is over-represented in CG-deficient organisms. We also describe exceptions for widely known exclusive words, such as CG and TA.


  Московский Государственный Университет имени М.В.Ломоносова

Почтовый адрес:
119991 г. Москва, ГСП-1, Ленинские горы МГУ 1, стр. 73,
Факультет биоинженерии и биоинформатики, комната 433.

Телефон / факс: +7 (495) 939-41-95
Справочная телефонов МГУ +7 (495) 939-10-00

E-mail: bioeng@genebee.msu.ru

© 2011 Факультет биоинженерии и биоинформатики
Московского Государственного Университета имени М.В.Ломоносова


- создание сайта, 2010